The short-term effects of caffeine typically happen about 30 minutes after consumption. They can last up to 6 hours, depending on the individual. SiS GO Energy + Caffeine Gel gives you a mental and physical energy boost before or during exercise. They're designed for long, tough endurance events when you're flagging and need an edge because carbohydrate depletion is a major cause of fatigue during exercise. Clean in the mouth, the gels are easy to digest and carry with you.

Caffeine can delay or prevent sleep and improves task performance during sleep deprivation. [54] Shift workers who use caffeine make fewer mistakes that could result from drowsiness. [55]Caffeine is a proven ergogenic aid in humans. [58] Caffeine improves athletic performance in aerobic (especially endurance sports) and anaerobic conditions. [58] Moderate doses of caffeine (around 5mg/kg [58]) can improve sprint performance, [59] cycling and running time trial performance, [58] endurance (i.e., it delays the onset of muscle fatigue and central fatigue), [58] [60] [61] and cycling power output. [58] Caffeine increases basal metabolic rate in adults. [62] [63] [64] Caffeine ingestion prior to aerobic exercise increases fat oxidation, particularly in persons with low physical fitness. [65] This article was amended on 8 July 2021 to include mention of the Turkish influence on early European coffeehouses.

Drinking or eating caffeine when taking other drugs can be unpredictable and increase your risk of harm. Caffeine and medicines Some analog substances have been created which mimic caffeine's properties with either function or structure or both. Of the latter group are the xanthines DMPX [210] and 8-chlorotheophylline, which is an ingredient in dramamine. Members of a class of nitrogen substituted xanthines are often proposed as potential alternatives to caffeine. [211] [ unreliable source?] Many other xanthine analogues constituting the adenosine receptor antagonist class have also been elucidated. [212] The Beta Fuel Dual Source Energy Gel is optimised with a brand new 1:0.8 ratio of 40g carbohydrate of maltodextrin to fructose, increasing the percentage of ingested carbohydrate that is oxidized (known as efficiency) from 62% to 74% when compared with a ratio of 2:1Caffeine overdose can result in a state of central nervous system overstimulation known as caffeine intoxication, a clinically significant temporary condition that develops during, or shortly after, the consumption of caffeine. [140] This syndrome typically occurs only after ingestion of large amounts of caffeine, well over the amounts found in typical caffeinated beverages and caffeine tablets (e.g., more than 400–500mg at a time). According to the DSM-5, caffeine intoxication may be diagnosed if five (or more) of the following symptoms develop after recent consumption of caffeine: restlessness, nervousness, excitement, insomnia, flushed face, diuresis, gastrointestinal disturbance, muscle twitching, rambling flow of thought and speech, tachycardia or cardiac arrhythmia, periods of inexhaustibility, and psychomotor agitation. [141] One thing to keep in mind is that caffeine may slightly raise blood pressure in some people. However, this effect is generally small (3–4 mmHg) and tends to fade for most individuals when they consume coffee regularly ( 32, 33, 34, 35). Birth control pills can extend the half-life of caffeine, requiring greater attention to caffeine consumption. [158] Medications For most of us, to be caffeinated to one degree or another has simply become baseline human consciousness. Something like 90% of humans ingest caffeine regularly, making it the most widely used psychoactive drug in the world, and the only one we routinely give to children (commonly in the form of fizzy drinks). Few of us even think of it as a drug, much less our daily use of it as an addiction. It’s so pervasive that it’s easy to overlook the fact that to be caffeinated is not baseline consciousness but, in fact, an altered state. It just happens to be a state that virtually all of us share, rendering it invisible.

Caffeine's biological half-life– the time required for the body to eliminate one-half of a dose– varies widely among individuals according to factors such as pregnancy, other drugs, liver enzyme function level (needed for caffeine metabolism) and age. In healthy adults, caffeine's half-life is between 3 and 7hours. [8] The half-life is decreased by 30-50% in adult male smokers, approximately doubled in women taking oral contraceptives, and prolonged in the last trimester of pregnancy. [126] In newborns the half-life can be 80hours or more, dropping very rapidly with age, possibly to less than the adult value by age 6 months. [126] The antidepressant fluvoxamine (Luvox) reduces the clearance of caffeine by more than 90%, and increases its elimination half-life more than tenfold; from 4.9hours to 56hours. [187]There is some evidence that people who drink a moderate amount of caffeine regularly might have a lower risk of: By the 15th century, coffee was being cultivated in east Africa and traded across the Arabian peninsula. Initially, the new drink was regarded as an aide to concentration and used by Sufis in Yemen to keep them from dozing off during their religious observances. (Tea, too, started out as a little helper for Buddhist monks striving to stay awake through long stretches of meditation.) Within a century, coffeehouses had sprung up in cities across the Arab world. In 1570 there were more than 600 of them in Constantinople alone, and they spread north and west with the Ottoman empire. The Beta Fuel Gel with Nootropics contains 1 gram of the amino acid L-taurine, 250 milligrams of Cognizin® to enhance information processing and 200 milligrams of caffeine with 200 milligrams of L-theanine, the amino acid which has been shown to increase subjective feelings of alertness, while reducing feelings of ‘jitters’ that you get with caffeine alone. USAGE: Because caffeine is a drug, if you stop consuming caffeine you may develop withdrawal syndrome. Symptoms usually start a day or two after stopping caffeine. These symptoms can last up to a week, and include: Drinking between 3–5 cups of coffee per day or more than 3 cups of tea per day may also reduce the risk of brain diseases such as Alzheimer’s and Parkinson’s by 28–60% ( 10, 11, 12, 13).

Smoking tobacco increases caffeine clearance by 56%. [156] Cigarette smoking induces the cytochrome P450 1A2 enzyme that breaks down caffeine, which may lead to increased caffeine tolerance and coffee consumption for regular smokers. [157] Birth control Tea contains more caffeine than coffee by dry weight. A typical serving, however, contains much less, since less of the product is used as compared to an equivalent serving of coffee. Also contributing to caffeine content are growing conditions, processing techniques, and other variables. Thus, teas contain varying amounts of caffeine. [231] It’s hard to imagine that the sort of political, cultural and intellectual ferment that bubbled up in the coffeehouses of both France and England in the 17th century would ever have developed in a tavern. The kind of magical thinking that alcohol sponsored in the medieval mind began to yield to a new spirit of rationalism and, a bit later, Enlightenment thinking. French historian Jules Michelet wrote: “Coffee, the sober drink, the mighty nourishment of the brain, which unlike other spirits, heightens purity and lucidity; coffee, which clears the clouds of the imagination and their gloomy weight; which illumines the reality of things suddenly with the flash of truth.”Liver protection. Coffee may reduce the risk of liver damage (cirrhosis) by as much as 84%. It may slow disease progression, improve treatment response, and lower the risk of premature death ( 37, 38). Cognitive psychologists sometimes talk in terms of two distinct types of consciousness: spotlight consciousness, which illuminates a single focal point of attention, making it very good for reasoning, and lantern consciousness, in which attention is less focused yet illuminates a broader field of attention. Young children tend to exhibit lantern consciousness; so do many people on psychedelics. This more diffuse form of attention lends itself to mind wandering, free association, and the making of novel connections – all of which can nourish creativity. By comparison, caffeine’s big contribution to human progress has been to intensify spotlight consciousness – the focused, linear, abstract and efficient cognitive processing more closely associated with mental work than play. This, more than anything else, is what made caffeine the perfect drug not only for the age of reason and the Enlightenment, but for the rise of capitalism, too. One review reports that after participants ingested 37.5–450 mg of caffeine, they had improved alertness, short-term recall, and reaction time ( 1). Boukhezra adds that for healthy adults consuming moderate amounts - up to 300-400 mg of caffeine a day - there is little or no evidence of health risks, and some evidence of health benefits. 400 mg caffeine equates to around four cups of coffee, ten cans of cola, or two energy drinks. Caffeine is also a common ingredient of soft drinks, such as cola, originally prepared from kola nuts. Soft drinks typically contain 0 to 55 milligrams of caffeine per 12 ounce (350mL) serving. [232] By contrast, energy drinks, such as Red Bull, can start at 80 milligrams of caffeine per serving. The caffeine in these drinks either originates from the ingredients used or is an additive derived from the product of decaffeination or from chemical synthesis. Guarana, a prime ingredient of energy drinks, contains large amounts of caffeine with small amounts of theobromine and theophylline in a naturally occurring slow-release excipient. [233] Other beverages